Events

This joint webinar will feature Michał Mączewski (CMKP), author of the paper “Impaired coronary flow reserve by hyperviscosity in a mouse model of non-light chain multiple myeloma: a mechanism of coronary flow impairment at the capillary level.” This work was recognized in The Year in Cardiovascular Medicine 2025: Top 10 Papers in Cardio-Oncology, underscoring its impact on advancing our understanding of coronary microvascular dysfunction.

Together with cutting-edge in vivo imaging approaches, this webinar will explore how real-time analysis of cardiac and vascular function can provide new insights into cardiovascular disease mechanisms.

Session 1: Heart Physiology and Coronary Flow Dynamics in Disease

Prof. Mączewski will present his work on heart failure, ischemia–reperfusion injury, and cardiovascular dysfunction, with a focus on how coronary flow regulation is altered under pathological conditions. His research leverages advanced in vivo models to investigate the mechanisms driving impaired cardiac performance and vascular dysfunction.

Session 2: Real-time In vivo Imaging of the Beating Heart

Prof. Pilhan Kim will introduce cutting-edge intravital imaging approaches for visualizing the beating heart at high spatiotemporal resolution. His session will highlight how two-photon and confocal microscopy enable real-time observation of cellular dynamics, and will also present the use of a tissue-motion stabilizer accessory to minimize cardiac motion artifacts, enabling stable and precise imaging of the beating heart.